fabian™ HFO Ventilator

fabian™ HFO Ventilator

The fabian™ HFO was designed from the ground up as a dedicated neonatal ventilator to meet the special needs of the smallest most vulnerable patients, down to 300g and 2cc tidal volumes. From NIV, to conventional ventilation, to HFOV, the fabian offers unparalleled flexibility for treating any neonatal patient anywhere in the hospital. The fabian HFO can also be equipped with smart algorithms to help optimize patient care, such as: Forced Oscillatory Technique (FOT), Volume Guarantee, and PRICO (Closed-Loop).

Please note, all products, services, or features of products and services may not be available in your local area. Please check with your local Vyaire representative. The information provided in this site is intended for healthcare professionals.


The challenge of optimal lung recruitment

FOT – Forced Oscillation Technique

The patented Forced Oscillation Technique (FOT) is a non-invasive, protective and easy method that allows the clinician to assess an optimally recruited lung at the bedside. Strategies for optimizing lung volume are critical – especially in preterm newborns. Usually, CPAP, PEEP and MAP are adjusted according to oxygenation, both in conventional modes and during High-Frequency Oscillatory Ventilation (HFOV). But oxygen saturation (SpO₂ or pO₂) may be an imperfect guide for MAP or PEEP titration: there remains a risk that PEEP-induced over-distension and intra-tidal recruitment/derecruitment go unnoticed.

An exclusive, patented option for the fabian:

FOT by setting the optimal CPAP, PEEP and MAP level for the individual patient, greatly reduces mechanical stress to the lungs, and brings down ventilation costs.

Direct feedback from the lung:

FOT allows the clinicians to assess the optimal mean airway pressure by measuring respiratory system reactance Xrs, and tailors protective HFOV or CMV ventilation support to the individual patient.

Author & Title
Therapy Comparison
Anna Lavizzari et al.
Changes in respiratory oscillatory mechanics of spontaneously breathing preterm infants receiving CPAP over the first day of life.
FOT allows to assess respiratory mechanics in non-cooperating subjects.
Non-invasive FOT assessment of lung mechanics in spontaneously breathing infants receiving CPAP is feasible and might provide relevant information for tailoring respiratory support assistance.
Roland Neumann et al.
Lung function assessment by forced oscillation technique for the prediction of pulmonary outcome in very preterm infants.
Prediction of respiratory outcome
FOT during non-invasive respiratory support was feasible and well tolerated, even in the first weeks of life. Xrs by FOT during the 1st week of life is significantly correlated with respiratory outcome. Xrs improves estimation of the duration of respiratory support compared to clinical parameters alone.
Raffaeli G.et al.
Role of Lung Function Monitoring by the Forced Oscillation Technique for Tailoring Ventilation and Weaning in Neonatal ECMO: New Insights from a Case Report
The use of the forced oscillation technique (FOT) to evaluate lung function during neonatal ECMO
FOT allows bedside monitoring of lung mechanics in clinical practice and … it may provide useful information for a patient tailored respiratory support strategy for ECMO patients and support clinicians in evaluating disease progression and identifying the optimal timing for ECMO weaning, thereby reducing the risk of premature or late decannulation, which can both lead to adverse outcomes.

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